alpha- synuclein Images for dNaga’s Proteinology with original music by Joel Davel

By February 15, 2017 Uncategorized No Comments
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You will find a full list of supporters and interviews at the end of this clip.

The following video was projected behind the dNaga dancers during their performance of Proteinology during the 2016 World Parkinson’s Congress. The three movies following the quotes were created by researchers studying alpha- synuclein and producing cutting edge findings in their field. The following citations for the movies are listed in the order shown.

Movie S1. 3D surface rendering of confocal Z-stacks of the SNCA−/− neuron. The 3D rendering establishes the intracellular nature of hα-Syn inclusions and reveals their close association with nuclear and cytoplasmic membranes. hα-Syn staining is shown in green, β3 tubulin staining (performed to reveal neurons) is shown in red, and nuclear staining (DAPI) is shown in blue. The surface rendering of hα-Syn staining and DAPI was performed using Imaris software.

We thank the Lashuel and Fares lab at the Brain Mind Institute at the Swiss Federal Institute of Technology Lausanne for sharing this movie with us from their 2016 PNAS publication:

Fares M-B, Maco B, Oueslati A, et al. Induction of de novo α-synuclein fibrillization in a neuronal model for Parkinson’s disease. Proceedings of the National Academy of Sciences of the United States of America. 2016; 113(7): E912-E921. doi:10.1073/pnas.1512876113.


Alpha synuclein movie. Derived from NMR structures of synuclein bound to vesicles.

We thank Dr. Brock Schuman at the Keenan Research Center for Biomedical Science of St. Michael’s Hospital in Toronto ON, Canada for sharing this movie with us.


Atomic-Resolution Structure of Alpha-Synuclein Fibrils.

We thank Dr. Chad Rienstra and Marcus Tuttle at the University of Illinois at Urbana-Champaign for sharing this movie with us from their 2016 Nature publication:

Tuttle MD, Comellas G, Nieuwkoop AJ, et al. Solid-state nmr structure of a pathogenic fibril of full-length human alpha-synuclein. Nat.Struct.Mol.Biol. 2016; 23(5): 409-15. doi: 10.1038/nsmb.3194.

About Claudine

Claudine Naganuma (Choreographer/Teacher) received a liberal arts education from Dominican College, earning a BA degree in English Literature. She studied Early Childhood Education while she earned an MFA in Dance from Mills College in Choreography and Performance(1992). Claudine taught at Aurora Elementary School in the fourth/fifth grade classroom and at La Escuelita in a sixth grade classroom doing a fall semester empowerment workshop. She is currently a ballet teacher and Director of Danspace and its Dance for PD® program since 2007. Claudine served as the Artistic Director of Asian American Dance Performances for twelve years. There, she had the opportunity to curate and produce Asian Pacific Islander (API) dance makers and lead its resident dance company, Unbound Spirit. Together with San Francisco Community Arts Organizations, the Asian Pacific Islander Cultural Center was founded to support contemporary API work. As a choreographer, Claudine has received a Young Presenters award from Jacob’s Pillow, a Jack Loftis and Vibeke Strand Honorary Fellowship as a Djerassi Artist in Resident. She was also selected as an international exchange artist between the Hong Kong Fringe Club and the Yerba Buena Center for the Arts. Claudine’s work was recently filmed as part of Dave Iverson’s documentary Capturing Grace. Her choreography set on the Mark Morris Dance Group’s Youth Company along with members of the Brooklyn Parkinson Group and dNaga performed at the World Parkinson Congress in September 2016. Claudine’s untiring dedication to the community is further evidenced by her GIRL project, now in its fourth year. This is a free art and empowerment workshop for middle school girls living in the San Antonio District of Oakland.

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